![]() Recombination events occur more frequently when community transmission levels are high. Recombinant virus: Viruses that occur when multiple variants infect the same individual at the same time and exchange genetic material with each other, changing their formulations. This term is sometimes used interchangeably with “subvariant.”Īncestral strain: The original form of SARS-CoV-2 identified in December 2019 often referred to elsewhere as the “original” or “Wuhan” strain. For example, Omicron BA.2 is an Omicron sublineage. Lineage: A group of closely related viruses with a common ancestor. This term is sometimes used interchangeably with “sublineage.” Subvariant: A subgroup of variants categorized based on genomic changes that they have in common and the time frame in which those changes appeared in tandem. Variant: A specific viral genome that contains one or more changes from the ancestral strain. Here we define key terms to discuss SARS-CoV-2 variants: ” Some variants are not associated with increased transmissibility or disease severity compared to the ancestral strain. Other variants could be more highly transmissible, cause more severe disease, or evade protection from therapeutics and/or vaccines, based on information about viral genomes or small-scale epidemiological studies, but these features may not be confirmed yet on a larger scale WHO designates these “ variants of interest. Some of these variants are more highly transmissible, cause more severe disease, or evade protection from therapeutics and/or vaccines these have been designated “ variants of concern ” by the World Health Organization. Scientists have identified numerous SARS-CoV-2 variants. Most mutations do not produce clinically relevant changes for individual infections, but occasionally mutations occur that may make the virus more infectious, cause more severe disease, evade the protection afforded by vaccines or therapeutics, or affect the sensitivity or specificity of diagnostic tools. Viruses including SARS-CoV-2 mutate over time, and as a result, new variants tend to emerge. Some sections may reflect more recent updates. Antigen multi-analyte respiratory panel tests authorized in the table below are assigned the QMN product code.This page undergoes regular review and was last comprehensively reviewed on February 24, 2023. To see additional authorization documents, such as letters granting EUA amendments or revisions, and a list of other brand names authorized under a specific EUA, select the plus (+) button beside the "Date EUA Issued or Last Updated" for each EUA.Īuthorized EUA devices in the table below for SARS-CoV-2 antigen diagnostic tests are assigned the QKP product code. more likely to continue to perform as labeled as new variants emerge.designed to detect more than one section of the proteins that make up SARS-CoV-2.Tests with "multiple targets" in the attribute column are: more susceptible to changes in performance due to viral mutations, meaning they are more likely to fail to detect new variants.designed to detect only one antigen target, currently either a section of the spike protein or a section of the nucleocapsid protein. ![]() Tests with "single target" in the attribute column are:
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